Vanadium compound



Patented Dec. 11,1928.

UNITED STATES rmNs HABL.

PATENT OFFICE.

a-Nnwaman xnorr, or ELBERFELD, GERMANY, ASSIGNORS TOWIN- manor cnnmrcan COMPANY, me, or NEW YORK, N.

, VANADIUM 'coMrouNn.

No Drawing. Application filed July 10, 1925, Serial No. 42,831, and in Germany September; 17, 1924.

The present invention concerns the pro-- duction of the hitherto unknown compounds of tetravalent vanadium with carboxylic acids, such as triglycollamic, tartaric acid, thioglycollic acid, salicylic acid, mandellc acid or the like. The new compounds have proved to be valuable remedies against syphilis.

They are after being dried and pulverized dark powders soluble in water. The aqueous solutions show no irritating action. They canv be employed for subcutaneous iniec- 4 solved. Subsequently 10 parts by weight of vanadium tetroxide are added and the migo ture is further heated for some time. After the reaction is complete, it is filtered and the filtrate is evaporated to dryness. The new product is a greyish powder having most probably the formula:

OH 000 I v-o GHr-COO NGH' 000 T- om-ooo being soluble in water. The analogous product obtalned from salicylic acid, sodium hydroxide and vanadium tetroxide has most probably the formula:

O-GqHr-COONa v O-GaHr-OOONEI o-oinroooNa O-QnHa-OOONB It is a. greyishbrown powder soluble in water 7 with a slightly alkaline reaction.

wherein V represents vanadium, O represents oxygen,. represents an organic carboxylic acidresidue; and M represents the residue of an inorganic base. i

3. As a new product, a compound of a salt of tetravalent vanadium with an organic carboxylic acid, having most probably the formula wherein V represents vanadium. and M represents the residue of an inorganic base.

4. The herein described new organic tetra-' valent vanadyl carboxylates having most probably the following formula V'(RM r wherein V represents a tetravalent vanadium radicle containing oxygen and R-M represents an inorganic basic salt of a residue of an organic carboxylic acid being grey-ish to greyish-brown powders readily soluble in water and valuable anti-syphilitics for sub v cutaneous use in aqueous solutions; substantially as described.

Tn testimony whereof we have hereunto .set our hands.

HANS HAHL. WALTER KROPP. 

